MiRNA 34-a regulate SIRT-1 and Foxo-1 expression in endometriosis

Title : Genetic polymorphisms at SIRT 1 and FOXO 1 are associated with carotid atherosclerosis in the SAPHIR cohort

CBP-mediated FOXO-1 acetylation inhibits pancreatic tumor growth by targeting SirT.

Here, we investigated the potential mechanism of capsaicin-mediated apoptosis in pancreatic cancer cells. Capsaicin treatment phosphorylated c-jun-NH2-kinase (JNK); forkhead box transcription factor, class O (FOXO1); and BIM in BxPC-3, AsPC-1, and L3.6PL cells. The expression of BIM increased in response to capsaicin treatment. Capsaicin treatment caused cleavage of caspase-3 and PARP, indicati...

Beta-boswellic acid and ethanolic extract of Olibanum regulate the expression levels of CREB-1 and CREB-2 genes

Physiological studies confirm improvement of memory by Olibanum, a resin from Boswellia species, while little is known about the molecular mechanism by which it affects memory performance. Two master transcription factors, CREB-1 and CREB-2, regulate downstream memory-related genes expression, leading to the long-term memory potentiation. This study addresses the effects of Beta-boswellic acid ...

The Expression of The Autophagy Gene Beclin-1 mRNA and Protein in Ectopic and Eutopic Endometrium of Patients with Endometriosis

SIRT 1 mRNA Expression May Be Associated with Energy Expenditure and Insulin Sensitivity Running title : SIRT 1 expression , energy expenditure and insulin sensitivity

1 Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland 2 Department of Clinical Radiology, University of Kuopio, Kuopio, Finland 3 Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, France 4 Laboratory of Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland 5 Department of...